Centrine is a drug for short term, in hospital use to treat vomiting, diarrhea and other gastrointestinal symptoms by relieving spasms in the gastrointestinal tract.  Centrine decreases the stomach's motility, acidity, and secretions.  Also decreases the colon's tone and contractions.

Side Effects

May see dry mouth, dry eyes, blurred vision, or difficulty urinating. 

Warnings/Contraindications

Do not use in patients who are hypersensitive (allergic) to it or other anticholinergic drugs.  Do not use with patients with glaucoma, stomach or intestinal obstruction, heart disease, infectious intestinal diseases, certain other intestinal diseases, urinary obstruction, myasthenia gravis, liver disease, hyperthyroidism, high blood pressure, prostate disease, or esophageal reflux.